Why is this test important?
This profile offers a comprehensive basic check with complete blood count, organ and electrolyte parameters, as well as central metabolism and cardiovascular markers. It is suitable for annual health screening and provides valuable information about common diseases such as diabetes, lipid metabolism disorders, blood formation disorders, or dysfunction of the liver, kidneys, and thyroid.
Included Parameters
Blood Count V
- Erythrocytes, hemoglobin, hematocrit: Assess the oxygen transport capacity of the blood. Reductions indicate anemia, elevations suggest dehydration or other diseases.
- MCV, MCH, MCHC, RDW: Describe the size, hemoglobin content, and variability of red blood cells. Deviations indicate iron deficiency, vitamin B12 or folate deficiency.
- Leukocytes: Total white blood cells. Elevated with infections/inflammation, reduced with bone marrow weakness or certain infections.
- Differential blood count (neutrophils, lymphocytes, monocytes, eosinophils, basophils – each absolute and in %): Detailed assessment of immune defense. Changes indicate infections, allergies, or immunological disorders.
- Platelets: Blood platelets, important for clotting. Deviations can lead to bleeding tendency or thrombosis risk.
Liver Health
- ASAT (AST), ALAT (ALT): Liver enzymes that rise when cells are damaged. Elevated with fatty liver, hepatitis, or medication burden.
- GGT: Sensitive marker for bile flow obstruction, alcohol or medication burden.
- Bilirubin total/direct: Hemoglobin breakdown product. Elevated with liver or bile duct diseases.
- Alkaline phosphatase (AP): Enzyme that rises with liver or bone disease.
- Albumin, total protein: Show the liver's protein synthesis capacity and nutritional status.
- Fib-4 (calculated): Risk calculator for liver fibrosis based on laboratory values.
Kidney & Electrolytes
- Creatinine and eGFR (creatinine-based): Standard marker of kidney function.
- Cystatin C and eGFR (Cystatin C): More sensitive marker, particularly more reliable in muscular or very lean individuals.
- Urea: End product of protein metabolism. Indication of kidney or metabolic stress.
- Sodium, potassium, calcium, phosphate: Central electrolytes for fluid balance, nerve conduction, muscle function, and bone metabolism. Deviations can trigger heart rhythm disturbances or muscle cramps.
- Uric acid: End product of purine metabolism. Elevated values are found in gout, overweight, insulin resistance, and kidney weakness.
Metabolism
- Glucose (fasting): Current blood sugar value. Elevated with diabetes or insulin resistance.
- HbA1c: Long-term marker for average blood sugar over the last 2–3 months.
- Insulin (fasting): Assesses insulin production. High values with normal blood sugar indicate insulin resistance.
- HOMA-IR: Calculated index from glucose and insulin to assess insulin sensitivity.
Heart Health
- LDL cholesterol: "Bad" cholesterol, central risk factor for atherosclerosis.
- HDL cholesterol: "Good" cholesterol that removes excess cholesterol from blood vessels.
- Non-HDL cholesterol: Encompasses all atherogenic cholesterol fractions.
- Total cholesterol: Sum of all cholesterol fractions, alone of limited specificity.
- Triglycerides: Blood fats that can be elevated with overweight, diabetes, or alcohol.
- Apolipoprotein B (ApoB): Exact marker for the number of atherogenic particles in the blood.
- Lipoprotein(a): Genetically determined risk factor for heart attack and stroke.
- hsCRP: High-sensitivity inflammation marker that indicates hidden chronic inflammation and cardiovascular risk.
Thyroid
- TSH: Control hormone of the thyroid. Deviations indicate over- or underfunction, before changes in T3 or T4 become apparent.
Practical Notes on Blood Collection
Blood collection should be performed fasting after 8–12 hours of fasting. Supplements (particularly vitamins and minerals) should not be taken the day before to avoid falsified results. Acute infections or strong physical stress can change inflammation values like hsCRP. For assessment of changes over time, annual repetition under comparable conditions is recommended.